Tried New...File, Folder, and Hyperlink - all behave the same way.

Tried refreshing the browser pages - IE11.

Checked permissions, etc, all the same as it was before.

IIS7.5
SQL Server 2012 Express
DNN 7.3.3 Community

Any ideas on what this could be? Thanks!

I'm getting some errors (f12 console), could be DNN... (but notice the XMLHttpRequest error)

HTML1300: Navigation occurred.
File: DocumentExchangeRoot.aspx
JQMIGRATE: Logging is active
HTML1423: Malformed start tag. Attributes should be separated by whitespace.
File: DocumentExchangeRoot.aspx, Line: 493, Column: 102
HTML1423: Malformed start tag. Attributes should be separated by whitespace.
File: DocumentExchangeRoot.aspx, Line: 493, Column: 143
HTML1423: Malformed start tag. Attributes should be separated by whitespace.
File: DocumentExchangeRoot.aspx, Line: 582, Column: 102
HTML1423: Malformed start tag. Attributes should be separated by whitespace.
File: DocumentExchangeRoot.aspx, Line: 582, Column: 143
HTML1500: Tag cannot be self-closing. Use an explicit closing tag.
File: DocumentExchangeRoot.aspx, Line: 1523, Column: 8
SEC7115: :visited and :link styles can only differ by color. Some styles were not applied to :visited.
File: DocumentExchangeRoot.aspx
SCRIPT7002: XMLHttpRequest: Network Error 0x2ee2, Could not complete the operation due to error 00002ee2.
File: DocumentExchangeRoot.aspx

DMX is 6.1.10

Are you using some form of output compression? What you could do is to contact us by email with a url and login because from this I cannot determine where the problem is. It's not a known issue in any case.